Publications

Ibrutinib Plus Venetoclax for First-Line Treatment of Chronic Lymphocytic Leukemia: Primary Analysis Results From the Minimal Residual Disease Cohort of the Randomized Phase II CAPTIVATE Study

Wierda WG, Allan JN, Siddiqi T, Kipps TJ, Opat S, Tedeschi A, Badoux XC, Kuss BJ, Jackson S, Moreno C, Jacobs R, Pagel JM, Flinn I, Pak Y, Zhou C, Szafer-Glusman E, Ninomoto J, Dean JP, James DF, Ghia P, Tam CS.

J Clin Oncol. 2021 Dec 1;39(34):3853-3865. doi: 10.1200/JCO.21.00807. Epub 2021 Oct 7.

Medical encounters at community-based physical activity events (parkrun) in the UK

Pedlar CR, Myrissa K, Barry M, Khwaja IG, Simpkin AJ, Newell J, Scarrott C, Whyte GP, Kipps C, Baggish AL.

Br J Sports Med. 2021 Dec;55(24):1420-1426. doi: 10.1136/bjsports-2021-104256. Epub 2021 Aug 4.

Successful Reduction of Postoperative Chest Tube Duration and Length of Stay After Congenital Heart Surgery: A Multicenter Collaborative Improvement Project

Bates KE, Connelly C, Khadr L, Graupe M, Hlavacek AM, Morell E, Pasquali SK, Russell JL, Schachtner SK, Strohacker C, Tanel RE, Ware AL, Wooton S, Madsen NL, Kipps AK.

J Am Heart Assoc. 2021 Nov 2;10(21):e020730. doi: 10.1161/JAHA.121.020730. Epub 2021 Oct 29.

Evidence to guide the optimal timing for pre-chemotherapy blood tests for early breast, colorectal cancer and diffuse large B-cell lymphoma

Chambers P, Wei L, Forster MD, Kipps E, Wong ICK, Jani Y.

Cancer Med. 2021 Nov;10(22):7996-8004. doi: 10.1002/cam4.4316. Epub 2021 Sep 28.

Phase 1 TRANSCEND CLL 004 study of lisocabtagene maraleucel in patients with relapsed/refractory CLL or SLL

Siddiqi T, Soumerai JD, Dorritie KA, Stephens DM, Riedell PA, Arnason JE, Kipps TJ, Gillenwater HH, Gong L, Yang L, Ogasawara K, Thorpe J, Wierda WG.

Blood. 2021 Oct 26:blood.2021011895. doi: 10.1182/blood.2021011895. Online ahead of print.

Activation of Notch and Myc signaling via B cell-restricted depletion of Dnmt3a generates a consistent murine model of chronic lymphocytic leukemia

Biran A, Yin S, Kretzmer H, Ten Hacken E, Parvin S, Lucas F, Uduman M, Gutierrez C, Dangle N, Billington L, Regis FF, Rassenti LZ, Mohammad A, Hoffmann GB, Stevenson K, Zheng M, Witten E, Fernandes S, Tausch E, Sun C, Stilgenbauer S, Brown JR, Kipps TJ, Aster JC, Gnirke A, Neuberg DS, Letai A, Wang L, Carrasco RD, Meissner A, Wu CJ.

Cancer Res. 2021 Oct 22:canres.CAN-21-1273-A.2021. doi: 10.1158/0008-5472.CAN-21-1273. Online ahead of print.

The impact of smoking cessation on multiple sclerosis disease progression

Rodgers J, Friede T, Vonberg FW, Constantinescu CS, Coles A, Chataway J, Duddy M, Emsley H, Ford H, Fisniku L, Galea I, Harrower T, Hobart J, Huseyin H, Kipps CM, Marta M, McDonnell GV, McLean B, Pearson OR, Rog D, Schmierer K, Sharrack B, Straukiene A, Wilson HC, Ford DV, Middleton RM, Nicholas R; MS Register group.

Brain. 2021 Oct 8:awab385. doi: 10.1093/brain/awab385. Online ahead of print.

Investigating the effect of mouth guard use on aerobic performance in amateur boxers

Ahmed I, Kipps C, Fine P.

Clin Exp Dent Res. 2021 Oct;7(5):888-893. doi: 10.1002/cre2.422. Epub 2021 Mar 29.

Early Functional Status After Surgery for Congenital Heart Disease: A Single-Center Retrospective Study

Han B, Yang JK, Ling AY, Ma M, Kipps AK, Shin AY, Beshish AG.

Pediatr Crit Care Med. 2021 Sep 29. doi: 10.1097/PCC.0000000000002838. Online ahead of print.

Efficacy of venetoclax plus rituximab for relapsed CLL: 5-year follow-up of continuous or limited- duration therapy

Ma S, Seymour JF, Brander DM, Kipps TJ, Choi MY, Anderson MA, Humphrey K, Al Masud A, Pesko J, Nandam R, Salem AH, Chyla B, Arzt J, Jacobson A, Kim SY, Roberts AW.

Blood. 2021 Sep 9;138(10):836-846. doi: 10.1182/blood.2020009578.

Exploring the pathways to chronic lymphocytic leukemia

Stevenson FK, Forconi F, Kipps TJ.

Blood. 2021 Sep 9;138(10):827-835. doi: 10.1182/blood.2020010029.

Long-term Follow-up of Patients with Relapsed or Refractory Non-Hodgkin Lymphoma Treated with Venetoclax in a Phase I, First-in-Human Study

Davids MS, Roberts AW, Kenkre VP, Wierda WG, Kumar A, Kipps TJ, Boyer M, Salem AH, Pesko JC, Arzt JA, Mantas M, Kim SY, Seymour JF.

Clin Cancer Res. 2021 Sep 1;27(17):4690-4695. doi: 10.1158/1078-0432.CCR-20-4842. Epub 2021 Jun 3.

Marching to the Beet: The effect of dietary nitrate supplementation on high altitude exercise performance and adaptation during a military trekking expedition

Marshall AR, Rimmer JE, Shah N, Bye K, Kipps C, Woods DR, O'Hara J, Boos CJ, Barlow M.

Nitric Oxide. 2021 Sep 1;113-114:70-77. doi: 10.1016/j.niox.2021.05.002. Epub 2021 May 27.

The 'hub and spoke model' for the management of surgical patients during the COVID-19 pandemic

Kasivisvanathan R, Tilney HS, Jhanji S, O'Mahony M, Gruber P, Nicol D, Morgan D, Kipps E, Rasheed S.

Int J Health Plann Manage. 2021 Sep;36(5):1397-1406. doi: 10.1002/hpm.3243. Epub 2021 May 27.

Phase II study of acalabrutinib in ibrutinib-intolerant patients with relapsed/refractory chronic lymphocytic leukemia

Rogers KA, Thompson PA, Allan JN, Coleman M, Sharman JP, Cheson BD, Jones D, Izumi R, Frigault MM, Quah C, Raman RK, Patel P, Wang MH, Kipps TJ.

Haematologica. 2021 Sep 1;106(9):2364-2373. doi: 10.3324/haematol.2020.272500.

Quality of Life Assessments in Individuals With Young-Onset Dementia and Their Caregivers

Dixit D, Spreadbury J, Orlando R, Hayward E, Kipps C.

J Geriatr Psychiatry Neurol. 2021 Sep;34(5):426-433. doi: 10.1177/0891988720933348. Epub 2020 Jul 9.

Akt and MAPK/ERK signaling regulate neurite extension in adult neural progenitor cells but do not directly mediate disruption of cytoskeletal structure and neurite dynamics by low-level silver nanoparticles

Spitzer N, Patterson KK, Kipps DW.

Toxicol In Vitro. 2021 Aug;74:105151. doi: 10.1016/j.tiv.2021.105151. Epub 2021 Mar 19.

Polygenic risk score and risk of monoclonal B-cell lymphocytosis in caucasians and risk of chronic lymphocytic leukemia (CLL) in African Americans

Kleinstern G, Weinberg JB, Parikh SA, Braggio E, Achenbach SJ, Robinson DP, Norman AD, Rabe KG, Boddicker NJ, Vachon CM, Lesnick CE, Call TG, Brander DM, Rassenti LZ, Kipps TJ, Olson JE, Cerhan JR, Kay NE, Furman RR, Hanson CA, Shanafelt TD, Slager SL.

Leukemia. 2021 Jul 20. doi: 10.1038/s41375-021-01344-9. Online ahead of print.

Mining the Microenvironment for Therapeutic Targets in Chronic Lymphocytic Leukemia

Kipps TJ.

Cancer J. 2021 Jul-Aug 01;27(4):306-313. doi: 10.1097/PPO.0000000000000536.

Impact of timing of adjuvant chemothapy for early breast cancer: the Royal Marsden Hospital experience

Okines AFC, Kipps E, Irfan T, Coakley M, Angelis V, Asare B, Mohammed K, Walsh G, Ring A, Johnston SRD, Parton M, Turner NC, Smith IE.

Br J Cancer. 2021 Jul;125(2):299-304. doi: 10.1038/s41416-021-01428-4. Epub 2021 May 20.

Longitudinal Single-Cell Dynamics of Chromatin Accessibility and Mitochondrial Mutations in Chronic Lymphocytic Leukemia Mirror Disease History

Penter L, Gohil SH, Lareau C, Ludwig LS, Parry EM, Huang T, Li S, Zhang W, Livitz D, Leshchiner I, Parida L, Getz G, Rassenti LZ, Kipps TJ, Brown JR, Davids MS, Neuberg DS, Livak KJ, Sankaran VG, Wu CJ.

Cancer Discov. 2021 Jun 10:10.1158/2159-8290.CD-21-0276. doi: 10.1158/2159-8290.CD-21-0276. Online ahead of print.

Genetic Polymorphisms Related to VO2max Adaptation Are Associated With Elite Rugby Union Status and Competitive Marathon Performance

Hall ECR, Almeida SS, Heffernan SM, Lockey SJ, Herbert AJ, Callus P, Day SH, Pedlar CR, Kipps C, Collins M, Pitsiladis YP, Bennett MA, Kilduff LP, Stebbings GK, Erskine RM, Williams AG.

Int J Sports Physiol Perform. 2021 Jun 4:1-7. doi: 10.1123/ijspp.2020-0856. Online ahead of print.

High Acuity Therapy Variation Across Pediatric Acute Care Cardiology Units: Results from the Pediatric Acute Care Cardiology Collaborative Hospital Surveys

Harahsheh AS, Kipps AK, Hart SA, Cassidy SC, Clabby ML, Hlavacek AM, Hoerst AK, Graupe MA, Madsen NL, Bakar AM, Del Grippo EL, Patel SS, Bost JE, Tanel RE; Pediatric Acute Care Cardiology Collaborative (PAC3).

Pediatr Cardiol. 2021 Jun;42(5):1074-1081. doi: 10.1007/s00246-021-02584-3. Epub 2021 Apr 4.

Head impact forces in blind football are greater in competition than training and increased cervical strength may reduce impact magnitude

Fitzpatrick D, Thompson P, Kipps C, Webborn N.

Int J Inj Contr Saf Promot. 2021 Jun;28(2):194-200. doi: 10.1080/17457300.2021.1905667. Epub 2021 Mar 30.

Wnt5a enhances proliferation of chronic lymphocytic leukemia and ERK1/2 phosphorylation via a ROR1/DOCK2-dependent mechanism

Hasan MK, Ghia EM, Rassenti LZ, Widhopf GF 2nd, Kipps TJ.

Leukemia. 2021 Jun;35(6):1621-1630. doi: 10.1038/s41375-020-01055-7. Epub 2020 Oct 23.

Prioritisation by FIT to mitigate the impact of delays in the 2-week wait colorectal cancer referral pathway during the COVID-19 pandemic: a UK modelling study

Loveday C, Sud A, Jones ME, Broggio J, Scott S, Gronthound F, Torr B, Garrett A, Nicol DL, Jhanji S, Boyce SA, Williams M, Barry C, Riboli E, Kipps E, McFerran E, Muller DC, Lyratzopoulos G, Lawler M, Abulafi M, Houlston RS, Turnbull C.

Gut. 2021 Jun;70(6):1053-1060. doi: 10.1136/gutjnl-2020-321650. Epub 2020 Aug 27.

miR-29 modulates CD40 signaling in chronic lymphocytic leukemia by targeting TRAF4: an axis affected by BCR inhibitors

Sharma S, Pavlasova GM, Seda V, Cerna KA, Vojackova E, Filip D, Ondrisova L, Sandova V, Kostalova L, Zeni PF, Borsky M, Oppelt J, Liskova K, Kren L, Janikova A, Pospisilova S, Fernandes SM, Shehata M, Rassenti LZ, Jaeger U, Doubek M, Davids MS, Brown JR, Mayer J, Kipps TJ, Mraz M.

Blood. 2021 May 6;137(18):2481-2494. doi: 10.1182/blood.2020005627.

Incidence of COVID-19 in patients with rheumatic disease: is prior health education more important than shielding advice during the pandemic?

Kipps S, Paul A, Vasireddy S.

Clin Rheumatol. 2021 Apr;40(4):1575-1579. doi: 10.1007/s10067-020-05494-6. Epub 2020 Nov 11.

Clinical characteristics and outcome of critically ill COVID-19 patients with acute kidney injury: a single centre cohort study

Lowe R, Ferrari M, Nasim-Mohi M, Jackson A, Beecham R, Veighey K, Cusack R, Richardson D, Grocott M, Levett D, Dushianthan A; University Hospital Southampton Critical Care Team and the REACT COVID investigators.

BMC Nephrol. 2021 Mar 15;22(1):92. doi: 10.1186/s12882-021-02296-z.

A hotspot mutation in transcription factor IKZF3 drives B cell neoplasia via transcriptional dysregulation

Lazarian G, Yin S, Ten Hacken E, Sewastianik T, Uduman M, Font-Tello A, Gohil SH, Li S, Kim E, Joyal H, Billington L, Witten E, Zheng M, Huang T, Severgnini M, Lefebvre V, Rassenti LZ, Gutierrez C, Georgopoulos K, Ott CJ, Wang L, Kipps TJ, Burger JA, Livak KJ, Neuberg DS, Baran-Marszak F, Cymbalista F, Carrasco RD, Wu CJ.

Cancer Cell. 2021 Mar 8;39(3):380-393.e8. doi: 10.1016/j.ccell.2021.02.003.

Impact of long-term ibrutinib treatment on circulating immune cells in previously untreated chronic lymphocytic leukemia

Solman IG, Blum LK, Burger JA, Kipps TJ, Dean JP, James DF, Mongan A.

Leuk Res. 2021 Mar;102:106520. doi: 10.1016/j.leukres.2021.106520. Epub 2021 Feb 5.

The added value of the advanced practice provider in paediatric acute care cardiology

Willis AJ, Hoerst A, Hart SA, Holbein D, Lowery K, Harahsheh AS, Kipps AK, Madsen N, Patel SS, Tanel RE; Paediatric Acute Care Cardiology Collaborative (PAC3).

Cardiol Young. 2021 Feb;31(2):248-251. doi: 10.1017/S1047951120003789. Epub 2020 Nov 4.

Research Evaluation Alongside Clinical Treatment in COVID-19 (REACT COVID-19): an observational and biobanking study

Burke H, Freeman A, Dushianthan A, Celinski M, Batchelor J, Phan H, Borca F, Kipps C, Thomas GJ, Faust SN, Sheard N, Williams S, Fitzpatrick P, Landers D, Wilkinson T.

BMJ Open. 2021 Jan 22;11(1):e043012. doi: 10.1136/bmjopen-2020-043012.

Recurrent XPO1 mutations alter pathogenesis of chronic lymphocytic leukemia

Walker JS, Hing ZA, Harrington B, Baumhardt J, Ozer HG, Lehman A, Giacopelli B, Beaver L, Williams K, Skinner JN, Cempre CB, Sun Q, Shacham S, Stromberg BR, Summers MK, Abruzzo LV, Rassenti L, Kipps TJ, Parikh S, Kay NE, Rogers KA, Woyach JA, Coppola V, Chook YM, Oakes C, Byrd JC, Lapalombella R.

J Hematol Oncol. 2021 Jan 15;14(1):17. doi: 10.1186/s13045-021-01032-2.

The Causes and Impact of Crisis for People with Parkinson's Disease: A Patient and Carer Perspective

Fearn S, Bartolomeu Pires S, Agarwal V, Roberts HC, Spreadbury J, Kipps C.

J Parkinsons Dis. 2021;11(4):1935-1945. doi: 10.3233/JPD-212641.

Preneoplastic Alterations Define CLL DNA Methylome and Persist through Disease Progression and Therapy

Kretzmer H, Biran A, Purroy N, Lemvigh C, Clement K, Gruber M, Gu H, Rassenti L, Mohammad AW, Lesnick C, Slager SL, Braggio E, Shanafelt TD, Kay NE, Fernandes S, Brown JR, Wang L, Li S, Livak KJ, Neuberg DS, Klages S, Timmermann B, Kipps TJ, Campo E, Gnirke A, Wu CJ, Meissner A.

Blood Cancer Discov. 2021 Jan;2(1):54-69. doi: 10.1158/2643-3230.BCD-19-0058. Epub 2020 Dec 3.

Target-Based Care: An Intervention to Reduce Variation in Postoperative Length of Stay

Shin AY, Rao IJ, Bassett HK, Chadwick W, Kim J, Kipps AK, Komra K, Loh L, Maeda K, Mafla M, Presnell L, Sharek PJ, Steffen KM, Scheinker D, Algaze CA.

J Pediatr. 2021 Jan;228:208-212. doi: 10.1016/j.jpeds.2020.09.017. Epub 2020 Sep 10.

Clinical nurse specialist's role in young-onset dementia care

Spreadbury JH, Kipps CM.

Br J Community Nurs. 2020 Dec 2;25(12):604-609. doi: 10.12968/bjcn.2020.25.12.604.

Venetoclax Plus Rituximab in Relapsed Chronic Lymphocytic Leukemia: 4-Year Results and Evaluation of Impact of Genomic Complexity and Gene Mutations From the MURANO Phase III Study

Kater AP, Wu JQ, Kipps T, Eichhorst B, Hillmen P, D'Rozario J, Assouline S, Owen C, Robak T, de la Serna J, Jaeger U, Cartron G, Montillo M, Dubois J, Eldering E, Mellink C, Van Der Kevie-Kersemaekers AM, Kim SY, Chyla B, Punnoose E, Bolen CR, Assaf ZJ, Jiang Y, Wang J, Lefebure M, Boyer M, Humphrey K, Seymour JF.

J Clin Oncol. 2020 Dec 1;38(34):4042-4054. doi: 10.1200/JCO.20.00948. Epub 2020 Sep 28.

Predictors for a dementia gene mutation based on gene-panel next-generation sequencing of a large dementia referral series

Koriath C, Kenny J, Adamson G, Druyeh R, Taylor W, Beck J, Quinn L, Mok TH, Dimitriadis A, Norsworthy P, Bass N, Carter J, Walker Z, Kipps C, Coulthard E, Polke JM, Bernal-Quiros M, Denning N, Thomas R, Raybould R, Williams J, Mummery CJ, Wild EJ, Houlden H, Tabrizi SJ, Rossor MN, Hummerich H, Warren JD, Rowe JB, Rohrer JD, Schott JM, Fox NC, Collinge J, Mead S.

Mol Psychiatry. 2020 Dec;25(12):3399-3412. doi: 10.1038/s41380-018-0224-0. Epub 2018 Oct 2.

The Stanford acute heart failure symptom score for patients hospitalized with heart failure

Almond CS, Chen S, Dykes JC, Kwong J, Burstein DS, Rosenthal DN, Kipps AK, Teuteberg J, Murray JM, Kaufman BD, Hollander SA, Profita E, Yarlagadda VY, Sacks LD, Chen CY.

J Heart Lung Transplant. 2020 Nov;39(11):1250-1259. doi: 10.1016/j.healun.2020.08.002. Epub 2020 Aug 8.

ACC/AHA/ASE/HRS/ISACHD/SCAI/SCCT/SCMR/SOPE 2020 Appropriate Use Criteria for Multimodality Imaging During the Follow-Up Care of Patients With Congenital Heart Disease: A Report of the American College of Cardiology Solution Set Oversight Committee and Appropriate Use Criteria Task Force, American Heart Association, American Society of Echocardiography, Heart Rhythm Society, International Society for Adult Congenital Heart Disease, Society for Cardiovascular Angiography and Interventions, Society of Cardiovascular Computed Tomography, Society for Cardiovascular Magnetic Resonance, and Society of Pediatric Echocardiography

Writing Group, Sachdeva R, Valente AM, Armstrong AK, Cook SC, Han BK, Lopez L, Lui GK, Pickard SS, Powell AJ; Rating Panel, Bhave NM, Sachdeva R, Valente AM, Pickard SS, Baffa JM, Banka P, Cohen SB, Glickstein JS, Kanter JP, Kanter RJ, Kim YY, Kipps AK, Latson LA, Lin JP, Parra DA, Rodriguez FH 3rd, Saarel EV, Srivastava S, Stephenson EA, Stout KK, Zaidi AN; Solution Set Oversight Committee, Gluckman TJ, Aggarwal NR, Bhave NM, Dehmer GJ, Gilbert ON, Kumbhani DJ, Price AL, Winchester DE, Gulati M; Appropriate Use Criteria Task Force, Dehmer GJ, Doherty JU, Bhave NM, Daugherty SL, Dean LS, Desai MY, Gillam LD, Mehrotra P, Sachdeva R, Winchester DE.

J Am Soc Echocardiogr. 2020 Oct;33(10):e1-e48. doi: 10.1016/j.echo.2020.04.026.

Ibrutinib restores immune cell numbers and function in first-line and relapsed/refractory chronic lymphocytic leukemia

Solman IG, Blum LK, Hoh HY, Kipps TJ, Burger JA, Barrientos JC, O'Brien S, Mulligan SP, Kay NE, Hillmen P, Byrd JC, Lal ID, Dean JP, Mongan A.

Leuk Res. 2020 Oct;97:106432. doi: 10.1016/j.leukres.2020.106432. Epub 2020 Aug 11.

Noninvasive ventilation for COVID-19-associated acute hypoxaemic respiratory failure: experience from a single centre

Sivaloganathan AA, Nasim-Mohi M, Brown MM, Abdul N, Jackson A, Fletcher SV, Gupta S, Grocott MPW, Dushianthan A; University Hospital Southampton Critical Care and Respiratory Medicine Teams and the REACT investigators; UHS Critical Care Clinical Team; UHS Respiratory Clinical Team; REACT Investigators.

Br J Anaesth. 2020 Oct;125(4):e368-e371. doi: 10.1016/j.bja.2020.07.008. Epub 2020 Jul 21.

Intensive Care Unit and Acute Care Unit Length of Stay After Congenital Heart Surgery

Hart SA, Tanel RE, Kipps AK, Hoerst AK, Graupe MA, Cassidy SC, Hlavacek AM, Clabby ML, Bush LB, Zhang W, Banerjee MM, Pasquali SK, Gaies M, Madsen N.

Ann Thorac Surg. 2020 Oct;110(4):1396-1403. doi: 10.1016/j.athoracsur.2020.01.033. Epub 2020 Feb 28.

A Rapid Electronic Cognitive Assessment Measure for Multiple Sclerosis: Validation of Cognitive Reaction, an Electronic Version of the Symbol Digit Modalities Test

Middleton RM, Pearson OR, Ingram G, Craig EM, Rodgers WJ, Downing-Wood H, Hill J, Tuite-Dalton K, Roberts C, Watson L, Ford DV, Nicholas R; UK MS Register Research Group.

J Med Internet Res. 2020 Sep 23;22(9):e18234. doi: 10.2196/18234.

Inflammatory phenotyping predicts clinical outcome in COVID-19

Burke H, Freeman A, Cellura DC, Stuart BL, Brendish NJ, Poole S, Borca F, Phan HTT, Sheard N, Williams S, Spalluto CM, Staples KJ, Clark TW, Wilkinson TMA; REACT COVID investigators.

Respir Res. 2020 Sep 22;21(1):245. doi: 10.1186/s12931-020-01511-z.

Distinct evolutionary paths in chronic lymphocytic leukemia during resistance to the graft-versus-leukemia effect

Bachireddy P, Ennis C, Nguyen VN, Gohil SH, Clement K, Shukla SA, Forman J, Barkas N, Freeman S, Bavli N, Elagina L, Leshchiner I, Mohammad AW, Mathewson ND, Keskin DB, Rassenti LZ, Kipps TJ, Brown JR, Getz G, Ho VT, Gnirke A, Neuberg D, Soiffer RJ, Ritz J, Alyea EP, Kharchenko PV, Wu CJ.

Sci Transl Med. 2020 Sep 16;12(561):eabb7661. doi: 10.1126/scitranslmed.abb7661.

Venetoclax plus obinutuzumab versus chlorambucil plus obinutuzumab for previously untreated chronic lymphocytic leukaemia (CLL14): follow-up results from a multicentre, open-label, randomised, phase 3 trial

Al-Sawaf O, Zhang C, Tandon M, Sinha A, Fink AM, Robrecht S, Samoylova O, Liberati AM, Pinilla-Ibarz J, Opat S, Sivcheva L, Le Dû K, Fogliatto LM, Niemann CU, Weinkove R, Robinson S, Kipps TJ, Tausch E, Schary W, Ritgen M, Wendtner CM, Kreuzer KA, Eichhorst B, Stilgenbauer S, Hallek M, Fischer K.

Lancet Oncol. 2020 Sep;21(9):1188-1200. doi: 10.1016/S1470-2045(20)30443-5.

Computer simulation of dementia care demand heterogeneity using hybrid simulation methods: improving population-level modelling with individual patient decline trajectories

Evenden D, Brailsford S, Kipps C, Roderick P, Walsh B; Alzheimer's Disease Neuroimaging Initiative.

Public Health. 2020 Sep;186:197-203. doi: 10.1016/j.puhe.2020.07.018. Epub 2020 Aug 27.

The impact of regional (99m)Tc-HMPAO single-photon-emission computed tomography (SPECT) imaging on clinician diagnostic confidence in a mixed cognitive impairment sample

Prosser AMJ, Tossici-Bolt L, Kipps CM.

Clin Radiol. 2020 Sep;75(9):714.e7-714.e14. doi: 10.1016/j.crad.2020.04.016. Epub 2020 Jun 4.

Clearance of interstitial fluid (ISF) and CSF (CLIC) group-part of Vascular Professional Interest Area (PIA): Cerebrovascular disease and the failure of elimination of Amyloid-β from the brain and retina with age and Alzheimer's disease-Opportunities for Therapy

Carare RO, Aldea R, Agarwal N, Bacskai BJ, Bechman I, Boche D, Bu G, Bulters D, Clemens A, Counts SE, de Leon M, Eide PK, Fossati S, Greenberg SM, Hamel E, Hawkes CA, Koronyo-Hamaoui M, Hainsworth AH, Holtzman D, Ihara M, Jefferson A, Kalaria RN, Kipps CM, Kanninen KM, Leinonen V, McLaurin J, Miners S, Malm T, Nicoll JAR, Piazza F, Paul G, Rich SM, Saito S, Shih A, Scholtzova H, Snyder H, Snyder P, Thormodsson FR, van Veluw SJ, Weller RO, Werring DJ, Wilcock D, Wilson MR, Zlokovic BV, Verma A.

Alzheimers Dement (Amst). 2020 Aug 3;12(1):e12053. doi: 10.1002/dad2.12053. eCollection 2020.

Effect of delays in the 2-week-wait cancer referral pathway during the COVID-19 pandemic on cancer survival in the UK: a modelling study

Sud A, Torr B, Jones ME, Broggio J, Scott S, Loveday C, Garrett A, Gronthoud F, Nicol DL, Jhanji S, Boyce SA, Williams M, Riboli E, Muller DC, Kipps E, Larkin J, Navani N, Swanton C, Lyratzopoulos G, McFerran E, Lawler M, Houlston R, Turnbull C.

Lancet Oncol. 2020 Aug;21(8):1035-1044. doi: 10.1016/S1470-2045(20)30392-2. Epub 2020 Jul 20.

NF-κB-p62-NRF2 survival signaling is associated with high ROR1 expression in chronic lymphocytic leukemia

Sanchez-Lopez E, Ghia EM, Antonucci L, Sharma N, Rassenti LZ, Xu J, Sun B, Kipps TJ, Karin M.

Cell Death Differ. 2020 Jul;27(7):2206-2216. doi: 10.1038/s41418-020-0496-1. Epub 2020 Jan 28.

Center Variation in Chest Tube Duration and Length of Stay After Congenital Heart Surgery

Bates KE, Madsen NL, Khadr L, Gao Z, Crawford K, Gaies M, Graupe M, Hanke SP, Hlavacek AM, Morell E, Pasquali SK, Russell JL, Schachtner SK, Tanel RE, Ware AL, Kipps AK.

Ann Thorac Surg. 2020 Jul;110(1):221-227. doi: 10.1016/j.athoracsur.2019.09.078. Epub 2019 Nov 21.

Patella dislocation: an online systematic video analysis of the mechanism of injury

Dewan V, Webb MSL, Prakash D, Malik A, Gella S, Kipps C.

Knee Surg Relat Res. 2020 May 27;32(1):24. doi: 10.1186/s43019-020-00031-w.

UK neurology response to the COVID-19 crisis

Mummery CJ, Kipps CM.

Clin Med (Lond). 2020 Apr 30;20(3):266-9. doi: 10.7861/clinmed.2020-0159. Online ahead of print.

A cross-trial comparison of single-agent ibrutinib versus chlorambucil-obinutuzumab in previously untreated patients with chronic lymphocytic leukemia or small lymphocytic lymphoma

Tedeschi A, Greil R, Demirkan F, Robak T, Moreno C, Barr PM, Anz B, Simpson D, Gaidano G, Bairey O, Stevens D, Gill D, Flinn IW, Kipps TJ, Burger JA, Lin J, Webb T, Fedorov V, Styles L, Gribben JG.

Haematologica. 2020 Apr;105(4):e164-e168. doi: 10.3324/haematol.2019.223743. Epub 2019 Aug 14.

Schedule-based Family-centered Rounds: A Novel Approach to Achieve High Nursing Attendance and Participation

Kipps AK, Albert MS, Bomher S, Cheung S, Feehan S, Kim J.

Pediatr Qual Saf. 2020 Mar 13;5(2):e265. doi: 10.1097/pq9.0000000000000265. eCollection 2020 Mar-Apr.

Aurora B induces epithelial-mesenchymal transition by stabilizing Snail1 to promote basal-like breast cancer metastasis

Zhang J, Lin X, Wu L, Huang JJ, Jiang WQ, Kipps TJ, Zhang S.

Oncogene. 2020 Mar;39(12):2550-2567. doi: 10.1038/s41388-020-1165-z. Epub 2020 Jan 29.

Long-term efficacy and safety of first-line ibrutinib treatment for patients with CLL/SLL: 5 years of follow-up from the phase 3 RESONATE-2 study

Burger JA, Barr PM, Robak T, Owen C, Ghia P, Tedeschi A, Bairey O, Hillmen P, Coutre SE, Devereux S, Grosicki S, McCarthy H, Simpson D, Offner F, Moreno C, Dai S, Lal I, Dean JP, Kipps TJ.

Leukemia. 2020 Mar;34(3):787-798. doi: 10.1038/s41375-019-0602-x. Epub 2019 Oct 18.

ACC/AHA/ASE/HRS/ISACHD/SCAI/SCCT/SCMR/SOPE 2020 Appropriate Use Criteria for Multimodality Imaging During the Follow-Up Care of Patients With Congenital Heart Disease: A Report of the American College of Cardiology Solution Set Oversight Committee and Appropriate Use Criteria Task Force, American Heart Association, American Society of Echocardiography, Heart Rhythm Society, International Society for Adult Congenital Heart Disease, Society for Cardiovascular Angiography and Interventions, Society of Cardiovascular Computed Tomography, Society for Cardiovascular Magnetic Resonance, and Society of Pediatric Echocardiography

Sachdeva R, Valente AM, Armstrong AK, Cook SC, Han BK, Lopez L, Lui GK, Pickard SS, Powell AJ, Bhave NM, Sachdeva R, Valente AM, Pickard SS, Baffa JM, Banka P, Cohen SB, Glickstein JS, Kanter JP, Kanter RJ, Kim YY, Kipps AK, Latson LA, Lin JP, Parra DA, Rodriguez FH 3rd, Saarel EV, Srivastava S, Stephenson EA, Stout KK, Zaidi AN.

J Am Coll Cardiol. 2020 Feb 18;75(6):657-703. doi: 10.1016/j.jacc.2019.10.002. Epub 2020 Jan 6.

Chronic Lymphocytic Leukemia/Small Lymphocytic Lymphoma, Version 4.2020, NCCN Clinical Practice Guidelines in Oncology

Wierda WG, Byrd JC, Abramson JS, Bilgrami SF, Bociek G, Brander D, Brown J, Chanan-Khan AA, Chavez JC, Coutre SE, Davis RS, Fletcher CD, Hill B, Kahl BS, Kamdar M, Kaplan LD, Khan N, Kipps TJ, Lim MS, Ma S, Malek S, Mato A, Mosse C, Shadman M, Siddiqi T, Stephens D, Sundaram S, Wagner N, Dwyer M, Sundar H.

J Natl Compr Canc Netw. 2020 Feb;18(2):185-217. doi: 10.6004/jnccn.2020.0006.

Concentration-Dependent Activity of Hydromethylthionine on Clinical Decline and Brain Atrophy in a Randomized Controlled Trial in Behavioral Variant Frontotemporal Dementia

Shiells H, Schelter BO, Bentham P, Baddeley TC, Rubino CM, Ganesan H, Hammel J, Vuksanovic V, Staff RT, Murray AD, Bracoud L, Wischik DJ, Riedel G, Gauthier S, Jia J, Moebius HJ, Hardlund J, Kipps CM, Kook K, Storey JMD, Harrington CR, Wischik CM.

J Alzheimers Dis. 2020;75(2):501-519. doi: 10.3233/JAD-191173.

Ibrutinib reduces obinutuzumab infusion-related reactions in patients with chronic lymphocytic leukemia and is associated with changes in plasma cytokine levels

Lujan JV, Lengerke-Diaz PA, Jacobs C, Moreno-Cortes EF, Ramirez-Segura CA, Choi MY, McCarthy C, Heinen A, Kipps TJ, Castro JE.

Haematologica. 2020 Jan;105(1):e22-e25. doi: 10.3324/haematol.2018.212597. Epub 2019 May 2.